| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20032510 | HPV | ENSG00000186868.18 | protein_coding | MAPT | No | No | 4137 | P10636 |
| TVIS20020548 | HPV | ENSG00000186868.18 | protein_coding | MAPT | No | No | 4137 | P10636 |
| TVIS20020549 | HPV | ENSG00000186868.18 | protein_coding | MAPT | No | No | 4137 | P10636 |
| TVIS20020550 | HPV | ENSG00000186868.18 | protein_coding | MAPT | No | No | 4137 | P10636 |
| TVIS20020551 | HPV | ENSG00000186868.18 | protein_coding | MAPT | No | No | 4137 | P10636 |
| TVIS20020552 | HPV | ENSG00000186868.18 | protein_coding | MAPT | No | No | 4137 | P10636 |
| TVIS20020553 | HPV | ENSG00000186868.18 | protein_coding | MAPT | No | No | 4137 | P10636 |
| TVIS44029619 | HTLV-1 | ENSG00000186868.18 | protein_coding | MAPT | No | No | 4137 | P10636 |
| TVIS44012031 | HTLV-1 | ENSG00000186868.18 | protein_coding | MAPT | No | No | 4137 | P10636 |
| TVIS44047698 | HTLV-1 | ENSG00000186868.18 | protein_coding | MAPT | No | No | 4137 | P10636 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MAPT |
|---|---|
| DrugBank ID | DB14914 |
| Drug Name | Flortaucipir F-18 |
| Target ID | BE0003474 |
| UniProt ID | P10636 |
| Regulation Type | binder |
| PubMed IDs | 31172290; 23411393; 27660144; 29278274 |
| Citations | Wang YT, Edison P: Tau Imaging in Neurodegenerative Diseases Using Positron Emission Tomography. Curr Neurol Neurosci Rep. 2019 Jun 6;19(7):45. doi: 10.1007/s11910-019-0962-7.@@Xia CF, Arteaga J, Chen G, Gangadharmath U, Gomez LF, Kasi D, Lam C, Liang Q, Liu C, Mocharla VP, Mu F, Sinha A, Su H, Szardenings AK, Walsh JC, Wang E, Yu C, Zhang W, Zhao T, Kolb HC: [(18)F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease. Alzheimers Dement. 2013 Nov;9(6):666-76. doi: 10.1016/j.jalz.2012.11.008. Epub 2013 Feb 12.@@Wooten DW, Guehl NJ, Verwer EE, Shoup TM, Yokell DL, Zubcevik N, Vasdev N, Zafonte RD, Johnson KA, El Fakhri G, Normandin MD: Pharmacokinetic Evaluation of the Tau PET Radiotracer (18)F-T807 ((18)F-AV-1451) in Human Subjects. J Nucl Med. 2017 Mar;58(3):484-491. doi: 10.2967/jnumed.115.170910. Epub 2016 Sep 22.@@Vermeiren C, Motte P, Viot D, Mairet-Coello G, Courade JP, Citron M, Mercier J, Hannestad J, Gillard M: The tau positron-emission tomography tracer AV-1451 binds with similar affinities to tau fibrils and monoamine oxidases. Mov Disord. 2018 Feb;33(2):273-281. doi: 10.1002/mds.27271. Epub 2017 Dec 26. |
| Groups | Approved; Investigational |
| Direct Classification | |
| SMILES | [18F]C1=CC=C(C=N1)C1=CC=C2C(NC3=C2C=NC=C3)=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL3545253 |
