| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44027303 | HTLV-1 | ENSG00000140675.13 | protein_coding | SLC5A2 | No | No | 6524 | P31639 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC5A2 |
|---|---|
| DrugBank ID | DB12236 |
| Drug Name | Bexagliflozin |
| Target ID | BE0004753 |
| UniProt ID | P31639 |
| Regulation Type | inhibitor |
| PubMed IDs | 21215314; 34292100 |
| Citations | Zhang W, Welihinda A, Mechanic J, Ding H, Zhu L, Lu Y, Deng Z, Sheng Z, Lv B, Chen Y, Roberge JY, Seed B, Wang YX: EGT1442, a potent and selective SGLT2 inhibitor, attenuates blood glucose and HbA(1c) levels in db/db mice and prolongs the survival of stroke-prone rats. Pharmacol Res. 2011 Apr;63(4):284-93. doi: 10.1016/j.phrs.2011.01.001. Epub 2011 Jan 5.@@Azzam O, Carnagarin R, Lugo-Gavidia LM, Nolde J, Matthews VB, Schlaich MP: Bexagliflozin for type 2 diabetes: an overview of the data. Expert Opin Pharmacother. 2021 Nov;22(16):2095-2103. doi: 10.1080/14656566.2021.1959915. Epub 2021 Jul 29. |
| Groups | Approved; Investigational |
| Direct Classification | Phenolic glycosides |
| SMILES | OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)C1=CC=C(Cl)C(CC2=CC=C(OCCOC3CC3)C=C2)=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1808388 |
