| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30058336 | HIV | ENSG00000017260.20 | protein_coding | ATP2C1 | No | No | 27032 | B4E2Q0 P98194 |
| TVIS30058337 | HIV | ENSG00000017260.20 | protein_coding | ATP2C1 | No | No | 27032 | B4E2Q0 P98194 |
| TVIS30058338 | HIV | ENSG00000017260.20 | protein_coding | ATP2C1 | No | No | 27032 | B4E2Q0 P98194 |
| TVIS30058339 | HIV | ENSG00000017260.20 | protein_coding | ATP2C1 | No | No | 27032 | B4E2Q0 P98194 |
| TVIS30058340 | HIV | ENSG00000017260.20 | protein_coding | ATP2C1 | No | No | 27032 | B4E2Q0 P98194 |
| TVIS30058341 | HIV | ENSG00000017260.20 | protein_coding | ATP2C1 | No | No | 27032 | B4E2Q0 P98194 |
| TVIS30058342 | HIV | ENSG00000017260.20 | protein_coding | ATP2C1 | No | No | 27032 | B4E2Q0 P98194 |
| TVIS30058343 | HIV | ENSG00000017260.20 | protein_coding | ATP2C1 | No | No | 27032 | B4E2Q0 P98194 |
| TVIS30058344 | HIV | ENSG00000017260.20 | protein_coding | ATP2C1 | No | No | 27032 | B4E2Q0 P98194 |
| TVIS30058345 | HIV | ENSG00000017260.20 | protein_coding | ATP2C1 | No | No | 27032 | B4E2Q0 P98194 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ATP2C1 |
|---|---|
| DrugBank ID | DB01236 |
| Drug Name | Sevoflurane |
| Target ID | BE0010002 |
| UniProt ID | P16615 |
| Regulation Type | inhibitor |
| PubMed IDs | 7499320; 16533663; 29310813; 7509043 |
| Citations | Lopez MM, Kosk-Kosicka D: How do volatile anesthetics inhibit Ca(2+)-ATPases? J Biol Chem. 1995 Nov 24;270(47):28239-45.@@Pinheiro AC, Gomez RS, Guatimosim C, Silva JH, Prado MA, Gomez MV: The effect of sevoflurane on intracellular calcium concentration from cholinergic cells. Brain Res Bull. 2006 Mar 31;69(2):147-52. doi: 10.1016/j.brainresbull.2005.11.016. Epub 2005 Dec 19.@@Liu TJ, Zhang JC, Gao XZ, Tan ZB, Wang JJ, Zhang PP, Cheng AB, Zhang SB: Effect of sevoflurane on the ATPase activity of hippocampal neurons in a rat model of cerebral ischemia-reperfusion injury via the cAMP-PKA signaling pathway. Kaohsiung J Med Sci. 2018 Jan;34(1):22-33. doi: 10.1016/j.kjms.2017.09.004. Epub 2017 Nov 14.@@Franks NP, Lieb WR: Molecular and cellular mechanisms of general anaesthesia. Nature. 1994 Feb 17;367(6464):607-14. doi: 10.1038/367607a0. |
| Groups | Approved; Vet_approved |
| Direct Classification | Dialkyl ethers |
| SMILES | FCOC(C(F)(F)F)C(F)(F)F |
| Pathways | |
| PharmGKB | PA451341 |
| ChEMBL | CHEMBL1200694 |
