| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10048740 | HBV | ENSG00000138061.13 | protein_coding | CYP1B1 | No | No | 1545 | Q16678 Q53TK1 |
| TVIS20045685 | HPV | ENSG00000138061.13 | protein_coding | CYP1B1 | No | No | 1545 | Q16678 Q53TK1 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CYP1B1 |
|---|---|
| DrugBank ID | DB07776 |
| Drug Name | Flavone |
| Target ID | BE0001111 |
| UniProt ID | Q16678 |
| Regulation Type | |
| PubMed IDs | 19563207; 21053930 |
| Citations | Shimada T, Tanaka K, Takenaka S, Foroozesh MK, Murayama N, Yamazaki H, Guengerich FP, Komori M: Reverse type I binding spectra of human cytochrome P450 1B1 induced by flavonoid, stilbene, pyrene, naphthalene, phenanthrene, and biphenyl derivatives that inhibit catalytic activity: a structure-function relationship study. Chem Res Toxicol. 2009 Jul;22(7):1325-33. doi: 10.1021/tx900127s.@@Shimada T, Tanaka K, Takenaka S, Murayama N, Martin MV, Foroozesh MK, Yamazaki H, Guengerich FP, Komori M: Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives. Chem Res Toxicol. 2010 Dec 20;23(12):1921-35. doi: 10.1021/tx100286d. |
| Groups | Approved; Experimental |
| Direct Classification | Flavones |
| SMILES | O=C1C=C(OC2=CC=CC=C12)C1=CC=CC=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL275638 |
