Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30026886HIVENSG00000135766.9protein_codingEGLN1NoNo54583Q9GZT9
R4SCQ0
TVIS30026887HIVENSG00000135766.9protein_codingEGLN1NoNo54583Q9GZT9
R4SCQ0
TVIS30026888HIVENSG00000135766.9protein_codingEGLN1NoNo54583Q9GZT9
R4SCQ0
TVIS20037422HPVENSG00000135766.9protein_codingEGLN1NoNo54583Q9GZT9
R4SCQ0
TVIS20047823HPVENSG00000135766.9protein_codingEGLN1NoNo54583Q9GZT9
R4SCQ0
TVIS20067207HPVENSG00000135766.9protein_codingEGLN1NoNo54583Q9GZT9
R4SCQ0
TVIS20048431HPVENSG00000135766.9protein_codingEGLN1NoNo54583Q9GZT9
R4SCQ0
TCGA Plot Options
Drug Information
GeneEGLN1
DrugBank IDDB11682
Drug NameDaprodustat
Target IDBE0002217
UniProt IDQ9GZT9
Regulation Typeinhibitor
PubMed IDs32880805; 33597868
CitationsDhillon S: Daprodustat: First Approval. Drugs. 2020 Sep;80(14):1491-1497. doi: 10.1007/s40265-020-01384-y.@@Zheng Q, Wang Y, Yang H, Sun L, Fu X, Wei R, Liu YN, Liu WJ: Efficacy and Safety of Daprodustat for Anemia Therapy in Chronic Kidney Disease Patients: A Systematic Review and Meta-Analysis. Front Pharmacol. 2021 Jan 12;11:573645. doi: 10.3389/fphar.2020.573645. eCollection 2020.
GroupsApproved; Investigational
Direct ClassificationN-acyl-alpha amino acids
SMILESOC(=O)CNC(=O)C1C(=O)N(C2CCCCC2)C(=O)N(C2CCCCC2)C1=O
Pathways
PharmGKBPA166280581
ChEMBLCHEMBL3544988