| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20068092 | HPV | ENSG00000186297.12 | protein_coding | GABRA5 | No | No | 2558 | P31644 |
| TVIS20068709 | HPV | ENSG00000186297.12 | protein_coding | GABRA5 | No | No | 2558 | P31644 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GABRA5 |
|---|---|
| DrugBank ID | DB00402 |
| Drug Name | Eszopiclone |
| Target ID | BE0000471 |
| UniProt ID | P31644 |
| Regulation Type | agonist |
| PubMed IDs | 19942638; 18973287 |
| Citations | Nutt DJ, Stahl SM: Searching for perfect sleep: the continuing evolution of GABAA receptor modulators as hypnotics. J Psychopharmacol. 2010 Nov;24(11):1601-12. doi: 10.1177/0269881109106927. Epub 2009 Nov 26.@@Hanson SM, Morlock EV, Satyshur KA, Czajkowski C: Structural requirements for eszopiclone and zolpidem binding to the gamma-aminobutyric acid type-A (GABAA) receptor are different. J Med Chem. 2008 Nov 27;51(22):7243-52. doi: 10.1021/jm800889m. |
| Groups | Approved; Investigational |
| Direct Classification | Cyclopyrrolones |
| SMILES | CN1CCN(CC1)C(=O)O[C@@H]1N(C(=O)C2=NC=CN=C12)C1=NC=C(Cl)C=C1 |
| Pathways | |
| PharmGKB | PA162630444 |
| ChEMBL | CHEMBL1522 |
