| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30005896 | HIV | ENSG00000186642.16 | protein_coding | PDE2A | No | No | 5138 | O00408 Q8IW54 |
| TVIS30005897 | HIV | ENSG00000186642.16 | protein_coding | PDE2A | No | No | 5138 | O00408 Q8IW54 |
| TVIS30030686 | HIV | ENSG00000186642.16 | protein_coding | PDE2A | No | No | 5138 | O00408 Q8IW54 |
| TVIS30030687 | HIV | ENSG00000186642.16 | protein_coding | PDE2A | No | No | 5138 | O00408 Q8IW54 |
| TVIS44000482 | HTLV-1 | ENSG00000186642.16 | protein_coding | PDE2A | No | No | 5138 | O00408 Q8IW54 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE2A |
|---|---|
| DrugBank ID | DB09273 |
| Drug Name | Doxofylline |
| Target ID | BE0002085 |
| UniProt ID | O00408 |
| Regulation Type | inhibitor |
| PubMed IDs | 22138191 |
| Citations | van Mastbergen J, Jolas T, Allegra L, Page CP: The mechanism of action of doxofylline is unrelated to HDAC inhibition, PDE inhibition or adenosine receptor antagonism. Pulm Pharmacol Ther. 2012 Feb;25(1):55-61. doi: 10.1016/j.pupt.2011.10.007. Epub 2011 Nov 25. |
| Groups | Experimental |
| Direct Classification | Xanthines |
| SMILES | CN1C2=C(N(CC3OCCO3)C=N2)C(=O)N(C)C1=O |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1527608 |
