| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30012093 | HIV | ENSG00000166501.14 | protein_coding | PRKCB | Yes | Yes | 5579 | P05771 |
| TVIS30015325 | HIV | ENSG00000166501.14 | protein_coding | PRKCB | Yes | Yes | 5579 | P05771 |
| TVIS30015326 | HIV | ENSG00000166501.14 | protein_coding | PRKCB | Yes | Yes | 5579 | P05771 |
| TVIS30015327 | HIV | ENSG00000166501.14 | protein_coding | PRKCB | Yes | Yes | 5579 | P05771 |
| TVIS30015328 | HIV | ENSG00000166501.14 | protein_coding | PRKCB | Yes | Yes | 5579 | P05771 |
| TVIS30006807 | HIV | ENSG00000166501.14 | protein_coding | PRKCB | Yes | Yes | 5579 | P05771 |
| TVIS30018359 | HIV | ENSG00000166501.14 | protein_coding | PRKCB | Yes | Yes | 5579 | P05771 |
| TVIS30086629 | HIV | ENSG00000166501.14 | protein_coding | PRKCB | Yes | Yes | 5579 | P05771 |
| TVIS30081250 | HIV | ENSG00000166501.14 | protein_coding | PRKCB | Yes | Yes | 5579 | P05771 |
| TVIS30040600 | HIV | ENSG00000166501.14 | protein_coding | PRKCB | Yes | Yes | 5579 | P05771 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PRKCB |
|---|---|
| DrugBank ID | DB14001 |
| Drug Name | alpha-Tocopherol succinate |
| Target ID | BE0000872 |
| UniProt ID | P05771 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 15184978; 11850093; 10644549 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Wigg SJ, Tare M, Forbes J, Cooper ME, Thomas MC, Coleman HA, Parkington HC, O'Brien RC: Early vitamin E supplementation attenuates diabetes-associated vascular dysfunction and the rise in protein kinase C-beta in mesenteric artery and ameliorates wall stiffness in femoral artery of Wistar rats. Diabetologia. 2004 Jun;47(6):1038-46. Epub 2004 Jun 8.@@Huang Y, Ishizuka T, Miura A, Kajita K, Ishizawa M, Kimura M, Yamamoto Y, Kawai Y, Morita H, Uno Y, Yasuda K: Effect of 1 alpha,25-dihydroxy vitamin D3 and vitamin E on insulin-induced glucose uptake in rat adipocytes. Diabetes Res Clin Pract. 2002 Mar;55(3):175-83.@@Ganz MB, Seftel A: Glucose-induced changes in protein kinase C and nitric oxide are prevented by vitamin E. Am J Physiol Endocrinol Metab. 2000 Jan;278(1):E146-52. |
| Groups | Approved; Nutraceutical; Vet_approved |
| Direct Classification | Vitamin E compounds |
| SMILES | [H][C@@](C)(CCCC(C)C)CCC[C@@]([H])(C)CCC[C@]1(C)CCC2=C(C)C(OC(=O)CCC(O)=O)=C(C)C(C)=C2O1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL81421 |
