| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30017655 | HIV | ENSG00000176974.22 | protein_coding | SHMT1 | No | No | 6470 | P34896 |
| TVIS20033629 | HPV | ENSG00000176974.22 | protein_coding | SHMT1 | No | No | 6470 | P34896 |
| TVIS44042347 | HTLV-1 | ENSG00000176974.22 | protein_coding | SHMT1 | No | No | 6470 | P34896 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SHMT1 |
|---|---|
| DrugBank ID | DB02800 |
| Drug Name | 5-hydroxymethyl-5,6-dihydrofolic acid |
| Target ID | BE0000331 |
| UniProt ID | P34896 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 10592235 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Experimental |
| Direct Classification | Glutamic acid and derivatives |
| SMILES | NC1=NC2=C(N(CO)[C@@H](CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=N2)C(=O)N1 |
| Pathways | |
| PharmGKB | |
| ChEMBL |
