| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20031236 | HPV | ENSG00000157764.14 | protein_coding | BRAF | Yes | No | 673 | P15056 |
| TVIS20062319 | HPV | ENSG00000157764.14 | protein_coding | BRAF | Yes | No | 673 | P15056 |
| TVIS44029013 | HTLV-1 | ENSG00000157764.14 | protein_coding | BRAF | Yes | No | 673 | P15056 |
| TVIS44025844 | HTLV-1 | ENSG00000157764.14 | protein_coding | BRAF | Yes | No | 673 | P15056 |
| TVIS44045695 | HTLV-1 | ENSG00000157764.14 | protein_coding | BRAF | Yes | No | 673 | P15056 |
| TVIS44045694 | HTLV-1 | ENSG00000157764.14 | protein_coding | BRAF | Yes | No | 673 | P15056 |
| TVIS44039660 | HTLV-1 | ENSG00000157764.14 | protein_coding | BRAF | Yes | No | 673 | P15056 |
| TVIS44039659 | HTLV-1 | ENSG00000157764.14 | protein_coding | BRAF | Yes | No | 673 | P15056 |
| TVIS44039369 | HTLV-1 | ENSG00000157764.14 | protein_coding | BRAF | Yes | No | 673 | P15056 |
Target Gene Table
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TCGA Plot Options
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Drug Information
▼
| Gene | BRAF |
|---|---|
| DrugBank ID | DB08881 |
| Drug Name | Vemurafenib |
| Target ID | BE0000634 |
| UniProt ID | P15056 |
| Regulation Type | inhibitor |
| PubMed IDs | 23094782 |
| Citations | Jordan EJ, Kelly CM: Vemurafenib for the treatment of melanoma. Expert Opin Pharmacother. 2012 Dec;13(17):2533-43. doi: 10.1517/14656566.2012.737780. Epub 2012 Oct 24. |
| Groups | Approved |
| Direct Classification | Aryl-phenylketones |
| SMILES | CCCS(=O)(=O)NC1=C(F)C(C(=O)C2=CNC3=NC=C(C=C23)C2=CC=C(Cl)C=C2)=C(F)C=C1 |
| Pathways | |
| PharmGKB | PA165946873 |
| ChEMBL | CHEMBL1229517 |
