Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30086569HIVENSG00000153956.17protein_codingCACNA2D1NoNo781E7ERK3
P54289
Q9UIU0
TVIS30067419HIVENSG00000153956.17protein_codingCACNA2D1NoNo781E7ERK3
P54289
Q9UIU0
TVIS30067420HIVENSG00000153956.17protein_codingCACNA2D1NoNo781E7ERK3
P54289
Q9UIU0
TVIS20032816HPVENSG00000153956.17protein_codingCACNA2D1NoNo781E7ERK3
P54289
Q9UIU0
TVIS20035102HPVENSG00000153956.17protein_codingCACNA2D1NoNo781E7ERK3
P54289
Q9UIU0
TVIS20032228HPVENSG00000153956.17protein_codingCACNA2D1NoNo781E7ERK3
P54289
Q9UIU0
TVIS20062235HPVENSG00000153956.17protein_codingCACNA2D1NoNo781E7ERK3
P54289
Q9UIU0
TVIS20062024HPVENSG00000153956.17protein_codingCACNA2D1NoNo781E7ERK3
P54289
Q9UIU0
TVIS20061567HPVENSG00000153956.17protein_codingCACNA2D1NoNo781E7ERK3
P54289
Q9UIU0
TVIS44016830HTLV-1ENSG00000153956.17protein_codingCACNA2D1NoNo781E7ERK3
P54289
Q9UIU0
TCGA Plot Options
Drug Information
GeneCACNA2D1
DrugBank IDDB01023
Drug NameFelodipine
Target IDBE0000691
UniProt IDP54289
Regulation Typeinhibitor
PubMed IDs11752352; 10525060; 17475903
CitationsChen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Furukawa T, Yamakawa T, Midera T, Sagawa T, Mori Y, Nukada T: Selectivities of dihydropyridine derivatives in blocking Ca(2+) channel subtypes expressed in Xenopus oocytes. J Pharmacol Exp Ther. 1999 Nov;291(2):464-73.@@Zahradnikova A, Minarovic I, Zahradnik I: Competitive and cooperative effects of Bay K8644 on the L-type calcium channel current inhibition by calcium channel antagonists. J Pharmacol Exp Ther. 2007 Aug;322(2):638-45. Epub 2007 May 2.
GroupsApproved; Investigational
Direct ClassificationDihydropyridinecarboxylic acids and derivatives
SMILESCCOC(=O)C1=C(C)NC(C)=C(C1C1=C(Cl)C(Cl)=CC=C1)C(=O)OC
PathwaysFelodipine Metabolism Pathway; Felodipine Action Pathway
PharmGKBPA449591
ChEMBLCHEMBL1480