| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30082479 | HIV | ENSG00000127022.16 | protein_coding | CANX | No | No | 821 | P27824 |
| TVIS44016430 | HTLV-1 | ENSG00000127022.16 | protein_coding | CANX | No | No | 821 | P27824 |
| TVIS44050448 | HTLV-1 | ENSG00000127022.16 | protein_coding | CANX | No | No | 821 | P27824 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CANX |
|---|---|
| DrugBank ID | DB13999 |
| Drug Name | Moroctocog alfa |
| Target ID | BE0001011 |
| UniProt ID | P27824 |
| Regulation Type | chaperone |
| PubMed IDs | 17139284; 17016423; 9525969; 15213841; 17899080; 9607108 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Pipe SW, Morris JA, Shah J, Kaufman RJ: Differential interaction of coagulation factor VIII and factor V with protein chaperones calnexin and calreticulin. J Biol Chem. 1998 Apr 3;273(14):8537-44.@@Becker S, Simpson JC, Pepperkok R, Heinz S, Herder C, Grez M, Seifried E, Tonn T: Confocal microscopy analysis of native, full length and B-domain deleted coagulation factor VIII trafficking in mammalian cells. Thromb Haemost. 2004 Jul;92(1):23-35.@@Srour MA, Grupp J, Aburubaiha Z, Albert T, Brondke H, Oldenburg J, Schwaab R: Modified expression of coagulation factor VIII by addition of a glycosylation site at the N terminus of the protein. Ann Hematol. 2008 Feb;87(2):107-12. Epub 2007 Sep 26.@@Kaufman RJ, Pipe SW, Tagliavacca L, Swaroop M, Moussalli M: Biosynthesis, assembly and secretion of coagulation factor VIII. Blood Coagul Fibrinolysis. 1997 Dec;8 Suppl 2:S3-14. |
| Groups | Approved |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL2109137 |
