| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10017640 | HBV | ENSG00000130816.17 | protein_coding | DNMT1 | Yes | No | 1786 | I6L9H2 P26358 |
| TVIS10041678 | HBV | ENSG00000130816.17 | protein_coding | DNMT1 | Yes | No | 1786 | I6L9H2 P26358 |
| TVIS10050115 | HBV | ENSG00000130816.17 | protein_coding | DNMT1 | Yes | No | 1786 | I6L9H2 P26358 |
| TVIS30012521 | HIV | ENSG00000130816.17 | protein_coding | DNMT1 | Yes | No | 1786 | I6L9H2 P26358 |
| TVIS30007412 | HIV | ENSG00000130816.17 | protein_coding | DNMT1 | Yes | No | 1786 | I6L9H2 P26358 |
| TVIS30002955 | HIV | ENSG00000130816.17 | protein_coding | DNMT1 | Yes | No | 1786 | I6L9H2 P26358 |
| TVIS30015668 | HIV | ENSG00000130816.17 | protein_coding | DNMT1 | Yes | No | 1786 | I6L9H2 P26358 |
| TVIS30002956 | HIV | ENSG00000130816.17 | protein_coding | DNMT1 | Yes | No | 1786 | I6L9H2 P26358 |
| TVIS30002957 | HIV | ENSG00000130816.17 | protein_coding | DNMT1 | Yes | No | 1786 | I6L9H2 P26358 |
| TVIS30012522 | HIV | ENSG00000130816.17 | protein_coding | DNMT1 | Yes | No | 1786 | I6L9H2 P26358 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | DNMT1 |
|---|---|
| DrugBank ID | DB12116 |
| Drug Name | Epigallocatechin gallate |
| Target ID | BE0000892 |
| UniProt ID | P26358 |
| Regulation Type | inhibitor |
| PubMed IDs | 14633667 |
| Citations | Fang MZ, Wang Y, Ai N, Hou Z, Sun Y, Lu H, Welsh W, Yang CS: Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res. 2003 Nov 15;63(22):7563-70. |
| Groups | Investigational |
| Direct Classification | Catechin gallates |
| SMILES | OC1=CC(O)=C2C[C@@H](OC(=O)C3=CC(O)=C(O)C(O)=C3)[C@H](OC2=C1)C1=CC(O)=C(O)C(O)=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL297453 |
