Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44051484HTLV-1ENSG00000130816.17protein_codingDNMT1YesNo1786I6L9H2
P26358
TVIS44051485HTLV-1ENSG00000130816.17protein_codingDNMT1YesNo1786I6L9H2
P26358
TVIS44051486HTLV-1ENSG00000130816.17protein_codingDNMT1YesNo1786I6L9H2
P26358
TVIS44047846HTLV-1ENSG00000130816.17protein_codingDNMT1YesNo1786I6L9H2
P26358
TCGA Plot Options
Drug Information
GeneDNMT1
DrugBank IDDB12116
Drug NameEpigallocatechin gallate
Target IDBE0000892
UniProt IDP26358
Regulation Typeinhibitor
PubMed IDs14633667
CitationsFang MZ, Wang Y, Ai N, Hou Z, Sun Y, Lu H, Welsh W, Yang CS: Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res. 2003 Nov 15;63(22):7563-70.
GroupsInvestigational
Direct ClassificationCatechin gallates
SMILESOC1=CC(O)=C2C[C@@H](OC(=O)C3=CC(O)=C(O)C(O)=C3)[C@H](OC2=C1)C1=CC(O)=C(O)C(O)=C1
Pathways
PharmGKB
ChEMBLCHEMBL297453