Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10001782HBVENSG00000105851.11protein_codingPIK3CGYesNo5294P48736
TVIS10023515HBVENSG00000105851.11protein_codingPIK3CGYesNo5294P48736
TVIS10030913HBVENSG00000105851.11protein_codingPIK3CGYesNo5294P48736
TVIS30013925HIVENSG00000105851.11protein_codingPIK3CGYesNo5294P48736
TVIS30020890HIVENSG00000105851.11protein_codingPIK3CGYesNo5294P48736
TCGA Plot Options
Drug Information
GenePIK3CG
DrugBank IDDB05552
Drug NameTG100-115
Target IDBE0001315
UniProt IDP48736
Regulation Typeinhibitor
PubMed IDs17685602
CitationsPalanki MS, Dneprovskaia E, Doukas J, Fine RM, Hood J, Kang X, Lohse D, Martin M, Noronha G, Soll RM, Wrasidlo W, Yee S, Zhu H: Discovery of 3,3'-(2,4-diaminopteridine-6,7-diyl)diphenol as an isozyme-selective inhibitor of PI3K for the treatment of ischemia reperfusion injury associated with myocardial infarction. J Med Chem. 2007 Sep 6;50(18):4279-94. doi: 10.1021/jm051056c. Epub 2007 Aug 9.
GroupsInvestigational
Direct Classification
SMILESNC1=NC(N)=C2N=C(C3=CC=CC(O)=C3)C(=NC2=N1)C1=CC(O)=CC=C1
Pathways
PharmGKB
ChEMBLCHEMBL230011