| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30042880 | HIV | ENSG00000141510.19 | protein_coding | TP53 | No | Yes | 7157 | A0A087WT22 A0A087WXZ1 A0A087X1Q1 H2EHT1 K7PPA8 P04637 |
| TVIS30042881 | HIV | ENSG00000141510.19 | protein_coding | TP53 | No | Yes | 7157 | A0A087WT22 A0A087WXZ1 A0A087X1Q1 H2EHT1 K7PPA8 P04637 |
| TVIS30042882 | HIV | ENSG00000141510.19 | protein_coding | TP53 | No | Yes | 7157 | A0A087WT22 A0A087WXZ1 A0A087X1Q1 H2EHT1 K7PPA8 P04637 |
| TVIS30042883 | HIV | ENSG00000141510.19 | protein_coding | TP53 | No | Yes | 7157 | A0A087WT22 A0A087WXZ1 A0A087X1Q1 H2EHT1 K7PPA8 P04637 |
| TVIS30042884 | HIV | ENSG00000141510.19 | protein_coding | TP53 | No | Yes | 7157 | A0A087WT22 A0A087WXZ1 A0A087X1Q1 H2EHT1 K7PPA8 P04637 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TP53 |
|---|---|
| DrugBank ID | DB14533 |
| Drug Name | Zinc chloride |
| Target ID | BE0003380 |
| UniProt ID | P04637 |
| Regulation Type | chaperone |
| PubMed IDs | 17327663; 29843463 |
| Citations | Wang Y, Rosengarth A, Luecke H: Structure of the human p53 core domain in the absence of DNA. Acta Crystallogr D Biol Crystallogr. 2007 Mar;63(Pt 3):276-81. Epub 2007 Feb 21.@@Kogan S, Carpizo DR: Zinc Metallochaperones as Mutant p53 Reactivators: A New Paradigm in Cancer Therapeutics. Cancers (Basel). 2018 May 29;10(6). pii: cancers10060166. doi: 10.3390/cancers10060166. |
| Groups | Approved; Investigational |
| Direct Classification | Transition metal chlorides |
| SMILES | [Cl-].[Cl-].[Zn++] |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1200679 |
