Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10046482HBVENSG00000010671.18protein_codingBTKYesNo695Q06187
Q5JY90
TVIS10057601HBVENSG00000010671.18protein_codingBTKYesNo695Q06187
Q5JY90
TVIS30021024HIVENSG00000010671.18protein_codingBTKYesNo695Q06187
Q5JY90
TCGA Plot Options
Drug Information
GeneBTK
DrugBank IDDB14785
Drug NameFenebrutinib
Target IDBE0001284
UniProt IDQ06187
Regulation Typeinhibitor
PubMed IDs33689480
CitationsZheng TJ, Lofurno ER, Melrose AR, Lakshmanan HHS, Pang J, Phillips KG, Fallon ME, Kohs TCL, Ngo ATP, Shatzel JJ, Hinds MT, McCarty OJT, Aslan JE: Assessment of the effects of Syk and BTK inhibitors on GPVI-mediated platelet signaling and function. Am J Physiol Cell Physiol. 2021 May 1;320(5):C902-C915. doi: 10.1152/ajpcell.00296.2020. Epub 2021 Mar 10.
GroupsInvestigational
Direct Classification
SMILESC[C@H]1CN(CCN1C1=CC=C(NC2=CC(=CN(C)C2=O)C2=C(CO)C(=NC=C2)N2CCN3C4=C(CC(C)(C)C4)C=C3C2=O)N=C1)C1COC1
Pathways
PharmGKB
ChEMBLCHEMBL4065122