| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS46000697 | BKPyv | ENSG00000198793.14 | protein_coding | MTOR | Yes | No | 2475 | P42345 |
| TVIS10004173 | HBV | ENSG00000198793.14 | protein_coding | MTOR | Yes | No | 2475 | P42345 |
| TVIS10025755 | HBV | ENSG00000198793.14 | protein_coding | MTOR | Yes | No | 2475 | P42345 |
| TVIS30001461 | HIV | ENSG00000198793.14 | protein_coding | MTOR | Yes | No | 2475 | P42345 |
| TVIS30074198 | HIV | ENSG00000198793.14 | protein_coding | MTOR | Yes | No | 2475 | P42345 |
| TVIS30022198 | HIV | ENSG00000198793.14 | protein_coding | MTOR | Yes | No | 2475 | P42345 |
| TVIS30022199 | HIV | ENSG00000198793.14 | protein_coding | MTOR | Yes | No | 2475 | P42345 |
| TVIS30022200 | HIV | ENSG00000198793.14 | protein_coding | MTOR | Yes | No | 2475 | P42345 |
| TVIS30022201 | HIV | ENSG00000198793.14 | protein_coding | MTOR | Yes | No | 2475 | P42345 |
| TVIS30022202 | HIV | ENSG00000198793.14 | protein_coding | MTOR | Yes | No | 2475 | P42345 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MTOR |
|---|---|
| DrugBank ID | DB06287 |
| Drug Name | Temsirolimus |
| Target ID | BE0002386 |
| UniProt ID | P42345 |
| Regulation Type | inhibitor |
| PubMed IDs | 18265991; 17935273; 11752352 |
| Citations | Patard JJ, Pouessel D, Bensalah K, Culine S: Targeted therapy in renal cell carcinoma. World J Urol. 2008 Apr;26(2):135-40. doi: 10.1007/s00345-008-0237-4. Epub 2008 Feb 12.@@Radulovic S, Bjelogrlic SK: Sunitinib, sorafenib and mTOR inhibitors in renal cancer. J BUON. 2007 Sep;12 Suppl 1:S151-62.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved |
| Direct Classification | Macrolide lactams |
| SMILES | OCC(C)(CO)C(=O)O[C@@H]1CC[C@@H](C[C@@H](C)[C@]2([H])CC(=O)[C@H](C)C=C(C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)C=CC=CC=C(C)[C@@H](OC)C[C@]3([H])CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)C[C@H]1OC |
| Pathways | |
| PharmGKB | PA164746890 |
| ChEMBL | CHEMBL1201182 |
