| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS46001147 | BKPyv | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS46001326 | BKPyv | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS42001156 | EBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10009443 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10009444 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10010334 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10007991 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10009525 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10010594 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10012210 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE3A |
|---|---|
| DrugBank ID | DB01427 |
| Drug Name | Amrinone |
| Target ID | BE0000436 |
| UniProt ID | Q14432 |
| Regulation Type | inhibitor |
| PubMed IDs | 11752352; 12076859; 19901885; 18468627 |
| Citations | Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Kobayashi T, Sugawara Y, Ohkubo T, Imamura H, Makuuchi M: Effects of amrinone on hepatic ischemia-reperfusion injury in rats. J Hepatol. 2002 Jul;37(1):31-8.@@Ko Y, Morita K, Nagahori R, Kinouchi K, Shinohara G, Kagawa H, Hashimoto K: Myocardial cyclic AMP augmentation with high-dose PDEIII inhibitor in terminal warm blood cardioplegia. Ann Thorac Cardiovasc Surg. 2009 Oct;15(5):311-7.@@Kucuk C, Akcan A, Akyyldyz H, Akgun H, Muhtaroglu S, Sozuer E: Effects of amrinone in an experimental model of hepatic ischemia-reperfusion injury. J Surg Res. 2009 Jan;151(1):74-9. doi: 10.1016/j.jss.2008.02.008. Epub 2008 Mar 13. |
| Groups | Approved |
| Direct Classification | Bipyridines and oligopyridines |
| SMILES | NC1=CC(=CNC1=O)C1=CC=NC=C1 |
| Pathways | |
| PharmGKB | PA164746803 |
| ChEMBL | CHEMBL12856 |
