Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10003611HBVENSG00000072062.16protein_codingPRKACAYesNo5566P17612
TVIS10007741HBVENSG00000072062.16protein_codingPRKACAYesNo5566P17612
TVIS10007742HBVENSG00000072062.16protein_codingPRKACAYesNo5566P17612
TVIS10021568HBVENSG00000072062.16protein_codingPRKACAYesNo5566P17612
TVIS10028209HBVENSG00000072062.16protein_codingPRKACAYesNo5566P17612
TVIS10044291HBVENSG00000072062.16protein_codingPRKACAYesNo5566P17612
TVIS10050253HBVENSG00000072062.16protein_codingPRKACAYesNo5566P17612
TVIS10050254HBVENSG00000072062.16protein_codingPRKACAYesNo5566P17612
TVIS30017339HIVENSG00000072062.16protein_codingPRKACAYesNo5566P17612
TVIS30048072HIVENSG00000072062.16protein_codingPRKACAYesNo5566P17612
TCGA Plot Options
Drug Information
GenePRKACA
DrugBank IDDB04522
Drug NameDexfosfoserine
Target IDBE0003761
UniProt IDP17612
Regulation Type
PubMed IDs17139284; 17016423; 10592235
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
GroupsExperimental
Direct ClassificationL-alpha-amino acids
SMILESN[C@@H](COP(O)(O)=O)C(O)=O
PathwaysDihydropyrimidine Dehydrogenase Deficiency (DHPD); 3-Phosphoglycerate Dehydrogenase Deficiency; Glycine and Serine Metabolism; Hyperglycinemia, Non-Ketotic; Non-Ketotic Hyperglycinemia; Sarcosinemia; Dimethylglycine Dehydrogenase Deficiency
PharmGKB
ChEMBLCHEMBL284377