Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20015299HPVENSG00000186350.12protein_codingRXRANoNo6256P19793
Q6P3U7
TVIS20067886HPVENSG00000186350.12protein_codingRXRANoNo6256P19793
Q6P3U7
TVIS20015177HPVENSG00000186350.12protein_codingRXRANoNo6256P19793
Q6P3U7
TVIS20026584HPVENSG00000186350.12protein_codingRXRANoNo6256P19793
Q6P3U7
TVIS20016513HPVENSG00000186350.12protein_codingRXRANoNo6256P19793
Q6P3U7
TVIS20030798HPVENSG00000186350.12protein_codingRXRANoNo6256P19793
Q6P3U7
TVIS44020094HTLV-1ENSG00000186350.12protein_codingRXRANoNo6256P19793
Q6P3U7
TVIS44022969HTLV-1ENSG00000186350.12protein_codingRXRANoNo6256P19793
Q6P3U7
TCGA Plot Options
Drug Information
GeneRXRA
DrugBank IDDB00755
Drug NameTretinoin
Target IDBE0000412
UniProt IDP19793
Regulation Typeagonist
PubMed IDs16946489; 9160172
CitationsMizuguchi Y, Wada A, Nakagawa K, Ito M, Okano T: Antitumoral activity of 13-demethyl or 13-substituted analogues of all-trans retinoic acid and 9-cis retinoic acid in the human myeloid leukemia cell line HL-60. Biol Pharm Bull. 2006 Sep;29(9):1803-9.@@Regazzi MB, Iacona I, Gervasutti C, Lazzarino M, Toma S: Clinical pharmacokinetics of tretinoin. Clin Pharmacokinet. 1997 May;32(5):382-402. doi: 10.2165/00003088-199732050-00004.
GroupsApproved; Investigational; Nutraceutical
Direct Classification
SMILESCC(C=CC1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
PathwaysRetinol Metabolism; Vitamin A Deficiency
PharmGKBPA164746900
ChEMBLCHEMBL38