Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10004450HBVENSG00000144285.24protein_codingSCN1ANoNo6323P35498
TVIS10014518HBVENSG00000144285.24protein_codingSCN1ANoNo6323P35498
TVIS10028748HBVENSG00000144285.24protein_codingSCN1ANoNo6323P35498
TVIS10044726HBVENSG00000144285.24protein_codingSCN1ANoNo6323P35498
TVIS10050751HBVENSG00000144285.24protein_codingSCN1ANoNo6323P35498
TVIS20037117HPVENSG00000144285.24protein_codingSCN1ANoNo6323P35498
TVIS20037956HPVENSG00000144285.24protein_codingSCN1ANoNo6323P35498
TVIS20031703HPVENSG00000144285.24protein_codingSCN1ANoNo6323P35498
TVIS20065419HPVENSG00000144285.24protein_codingSCN1ANoNo6323P35498
TVIS20055383HPVENSG00000144285.24protein_codingSCN1ANoNo6323P35498
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Drug Information
GeneSCN1A
DrugBank IDDB00907
Drug NameCocaine
Target IDBE0004901
UniProt IDQ8IWT1
Regulation Typeinhibitor
PubMed IDs9876137; 2155033
CitationsWright SN, Wang SY, Xiao YF, Wang GK: State-dependent cocaine block of sodium channel isoforms, chimeras, and channels coexpressed with the beta1 subunit. Biophys J. 1999 Jan;76(1 Pt 1):233-45.@@Crumb WJ Jr, Clarkson CW: Characterization of cocaine-induced block of cardiac sodium channels. Biophys J. 1990 Mar;57(3):589-99. doi: 10.1016/S0006-3495(90)82574-1.
GroupsApproved; Illicit
Direct ClassificationBenzoic acid esters
SMILES[H][C@]12CC[C@]([H])([C@H]([C@H](C1)OC(=O)C1=CC=CC=C1)C(=O)OC)N2C
PathwaysCocaine Action Pathway
PharmGKBPA449072
ChEMBLCHEMBL370805