| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10014315 | HBV | ENSG00000081248.13 | protein_coding | CACNA1S | No | No | 779 | B1ALM3 Q13698 |
| TVIS10014316 | HBV | ENSG00000081248.13 | protein_coding | CACNA1S | No | No | 779 | B1ALM3 Q13698 |
| TVIS30087325 | HIV | ENSG00000081248.13 | protein_coding | CACNA1S | No | No | 779 | B1ALM3 Q13698 |
| TVIS30026316 | HIV | ENSG00000081248.13 | protein_coding | CACNA1S | No | No | 779 | B1ALM3 Q13698 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CACNA1S |
|---|---|
| DrugBank ID | DB01388 |
| Drug Name | Mibefradil |
| Target ID | BE0002355 |
| UniProt ID | Q13698 |
| Regulation Type | inhibitor |
| PubMed IDs | 10372226; 10665814; 16899990 |
| Citations | Mocanu MM, Gadgil S, Yellon DM, Baxter GF: Mibefradil, a T-type and L-type calcium channel blocker, limits infarct size through a glibenclamide-sensitive mechanism. Cardiovasc Drugs Ther. 1999 Apr;13(2):115-22.@@Jimenez C, Bourinet E, Leuranguer V, Richard S, Snutch TP, Nargeot J: Determinants of voltage-dependent inactivation affect Mibefradil block of calcium channels. Neuropharmacology. 2000;39(1):1-10.@@Lee TS, Kaku T, Takebayashi S, Uchino T, Miyamoto S, Hadama T, Perez-Reyes E, Ono K: Actions of mibefradil, efonidipine and nifedipine block of recombinant T- and L-type Ca channels with distinct inhibitory mechanisms. Pharmacology. 2006;78(1):11-20. Epub 2006 Aug 7. |
| Groups | Investigational; Withdrawn |
| Direct Classification | Tetralins |
| SMILES | COCC(=O)O[C@]1(CCN(C)CCCC2=NC3=CC=CC=C3N2)CCC2=C(C=CC(F)=C2)[C@@H]1C(C)C |
| Pathways | |
| PharmGKB | PA450492 |
| ChEMBL | CHEMBL45816 |
