Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10005041HBVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS10005042HBVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS10034071HBVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS10051034HBVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS10050959HBVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS30086592HIVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS30086040HIVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS30083783HIVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS30063832HIVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS30063833HIVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TCGA Plot Options
Drug Information
GeneGRIA1
DrugBank IDDB04982
Drug NameTalampanel
Target IDBE0000640
UniProt IDP42261
Regulation Type
PubMed IDs12581229; 17199027; 16861112
CitationsLangan YM, Lucas R, Jewell H, Toublanc N, Schaefer H, Sander JW, Patsalos PN: Talampanel, a new antiepileptic drug: single- and multiple-dose pharmacokinetics and initial 1-week experience in patients with chronic intractable epilepsy. Epilepsia. 2003 Jan;44(1):46-53.@@Howes JF, Bell C: Talampanel. Neurotherapeutics. 2007 Jan;4(1):126-9.@@Denes L, Szilagyi G, Gal A, Nagy Z: Talampanel a non-competitive AMPA-antagonist attenuates caspase-3 dependent apoptosis in mouse brain after transient focal cerebral ischemia. Brain Res Bull. 2006 Jul 31;70(3):260-2. Epub 2006 Mar 31.
GroupsInvestigational
Direct ClassificationBenzodiazepines
SMILESC[C@@H]1CC2=CC3=C(OCO3)C=C2C(=NN1C(C)=O)C1=CC=C(N)C=C1
Pathways
PharmGKB
ChEMBLCHEMBL61872