| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10016573 | HBV | ENSG00000102468.11 | protein_coding | HTR2A | No | No | 3356 | P28223 |
| TVIS44041305 | HTLV-1 | ENSG00000102468.11 | protein_coding | HTR2A | No | No | 3356 | P28223 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HTR2A |
|---|---|
| DrugBank ID | DB00370 |
| Drug Name | Mirtazapine |
| Target ID | BE0000451 |
| UniProt ID | P28223 |
| Regulation Type | antagonist |
| PubMed IDs | 11063897; 17067560; 15309042 |
| Citations | Waldinger MD, Berendsen HH, Schweitzer DH: Treatment of hot flushes with mirtazapine: four case reports. Maturitas. 2000 Oct 31;36(3):165-8.@@Pawlyk AC, Cosmi S, Alfinito PD, Maswood N, Deecher DC: Effects of the 5-HT2A antagonist mirtazapine in rat models of thermoregulation. Brain Res. 2006 Dec 6;1123(1):135-44. doi: 10.1016/j.brainres.2006.09.050. Epub 2006 Oct 24.@@Celada P, Puig M, Amargos-Bosch M, Adell A, Artigas F: The therapeutic role of 5-HT1A and 5-HT2A receptors in depression. J Psychiatry Neurosci. 2004 Jul;29(4):252-65. |
| Groups | Approved |
| Direct Classification | Piperazinoazepines |
| SMILES | CN1CCN2C(C1)C1=CC=CC=C1CC1=C2N=CC=C1 |
| Pathways | Mirtazapine H1-Antihistamine Action |
| PharmGKB | PA450522 |
| ChEMBL | CHEMBL654 |
