| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20006788 | HPV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS20050635 | HPV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS20050286 | HPV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS20018566 | HPV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS20050919 | HPV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS20034063 | HPV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS20045082 | HPV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS44009720 | HTLV-1 | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS44033961 | HTLV-1 | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS44049462 | HTLV-1 | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE3A |
|---|---|
| DrugBank ID | DB04880 |
| Drug Name | Enoximone |
| Target ID | BE0000436 |
| UniProt ID | Q14432 |
| Regulation Type | inhibitor |
| PubMed IDs | 17714066; 16987374 |
| Citations | Boldt J, Suttner S: Combined use of ultra-short acting beta-blocker esmolol and intravenous phosphodiesterase 3 inhibitor enoximone. Expert Opin Pharmacother. 2007 Sep;8(13):2135-47.@@Sandroni C, Cavallaro F, Caricato A, Scapigliati A, Fenici P, Antonelli M: Enoximone in cardiac arrest caused by propranolol: two case reports. Acta Anaesthesiol Scand. 2006 Jul;50(6):759-61. |
| Groups | Approved; Investigational |
| Direct Classification | Aryl-phenylketones |
| SMILES | CSC1=CC=C(C=C1)C(=O)C1=C(C)NC(=O)N1 |
| Pathways | |
| PharmGKB | PA164768794 |
| ChEMBL | CHEMBL249856 |
