| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS42001190 | EBV | ENSG00000067225.21 | protein_coding | PKM | No | No | 5315 | B4DNK4 P14618 |
| TVIS10000226 | HBV | ENSG00000067225.21 | protein_coding | PKM | No | No | 5315 | B4DNK4 P14618 |
| TVIS10000227 | HBV | ENSG00000067225.21 | protein_coding | PKM | No | No | 5315 | B4DNK4 P14618 |
| TVIS30038850 | HIV | ENSG00000067225.21 | protein_coding | PKM | No | No | 5315 | B4DNK4 P14618 |
| TVIS44009276 | HTLV-1 | ENSG00000067225.21 | protein_coding | PKM | No | No | 5315 | B4DNK4 P14618 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PKM |
|---|---|
| DrugBank ID | DB11263 |
| Drug Name | Polydatin |
| Target ID | BE0000088 |
| UniProt ID | P14618 |
| Regulation Type | inhibitor |
| PubMed IDs | 26951145 |
| Citations | Ye X, Sun Y, Xu Y, Chen Z, Lu S: Integrated In Silico-In Vitro Discovery of Lung Cancer-related Tumor Pyruvate Kinase M2 (PKM2) Inhibitors. Med Chem. 2016;12(7):613-620. doi: 10.2174/1573406412666160307151535. |
| Groups | Approved |
| Direct Classification | Stilbene glycosides |
| SMILES | OC[C@H]1O[C@@H](OC2=CC(C=CC3=CC=C(O)C=C3)=CC(O)=C2)[C@H](O)[C@@H](O)[C@@H]1O |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL142652 |
