| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10018233 | HBV | ENSG00000110092.4 | protein_coding | CCND1 | Yes | No | 595 | P24385 Q6FI00 |
| TVIS10020609 | HBV | ENSG00000110092.4 | protein_coding | CCND1 | Yes | No | 595 | P24385 Q6FI00 |
| TVIS10020610 | HBV | ENSG00000110092.4 | protein_coding | CCND1 | Yes | No | 595 | P24385 Q6FI00 |
| TVIS10020608 | HBV | ENSG00000110092.4 | protein_coding | CCND1 | Yes | No | 595 | P24385 Q6FI00 |
| TVIS10051928 | HBV | ENSG00000110092.4 | protein_coding | CCND1 | Yes | No | 595 | P24385 Q6FI00 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CCND1 |
|---|---|
| DrugBank ID | DB00945 |
| Drug Name | Acetylsalicylic acid |
| Target ID | BE0001027 |
| UniProt ID | P24385 |
| Regulation Type | downregulator |
| PubMed IDs | 10993886; 28415819; 29218104 |
| Citations | Law BK, Waltner-Law ME, Entingh AJ, Chytil A, Aakre ME, Norgaard P, Moses HL: Salicylate-induced growth arrest is associated with inhibition of p70s6k and down-regulation of c-myc, cyclin D1, cyclin A, and proliferating cell nuclear antigen. J Biol Chem. 2000 Dec 8;275(49):38261-7. doi: 10.1074/jbc.M005545200.@@Cheng R, Liu YJ, Cui JW, Yang M, Liu XL, Li P, Wang Z, Zhu LZ, Lu SY, Zou L, Wu XQ, Li YX, Zhou Y, Fang ZY, Wei W: Aspirin regulation of c-myc and cyclinD1 proteins to overcome tamoxifen resistance in estrogen receptor-positive breast cancer cells. Oncotarget. 2017 May 2;8(18):30252-30264. doi: 10.18632/oncotarget.16325.@@Fan W, Li J, Chen J, Zhu L, Wang Y, Sun B, Hua B, Guo C, Yan Z: Aspirin inhibits the proliferation of synovium-derived mesenchymal stem cells by arresting the cell cycle in the G0/G1 phase. Am J Transl Res. 2017 Nov 15;9(11):5056-5062. eCollection 2017. |
| Groups | Approved; Vet_approved |
| Direct Classification | Acylsalicylic acids |
| SMILES | CC(=O)OC1=CC=CC=C1C(O)=O |
| Pathways | Acetylsalicylic Acid Action Pathway |
| PharmGKB | PA448497 |
| ChEMBL | CHEMBL25 |
