| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44034617 | HTLV-1 | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
| TVIS44035802 | HTLV-1 | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CFTR |
|---|---|
| DrugBank ID | DB00171 |
| Drug Name | ATP |
| Target ID | BE0001195 |
| UniProt ID | P13569 |
| Regulation Type | cofactor |
| PubMed IDs | 15623556 |
| Citations | Berger AL, Ikuma M, Welsh MJ: Normal gating of CFTR requires ATP binding to both nucleotide-binding domains and hydrolysis at the second nucleotide-binding domain. Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):455-60. Epub 2004 Dec 27. |
| Groups | Investigational; Nutraceutical |
| Direct Classification | Purine ribonucleoside triphosphates |
| SMILES | NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |
| Pathways | Glycerolipid Metabolism; Fatty Acid Metabolism; Pamidronate Action Pathway; Simvastatin Action Pathway; Citric Acid Cycle; Glutamate Metabolism; Argininosuccinic Aciduria; Gluconeogenesis; Betaine Metabolism; Butyrate Metabolism; 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency; Rosuvastatin Action Pathway; Propanoate Metabolism; Pentose Phosphate Pathway; Pyruvate Metabolism; Inositol Metabolism; Zoledronate Action Pathway; Glycine and Serine Metabolism; Selenoamino Acid Metabolism; Thiamine Metabolism; Pyrimidine Metabolism; Carbamoyl Phosphate Synthetase Deficiency; Ammonia Recycling; Histidine Metabolism; Pravastatin Action Pathway; Arginine and Proline Metabolism; Starch and Sucrose Metabolism; Purine Metabolism; Fluvastatin Action Pathway; Galactose Metabolism |
| PharmGKB | PA164743471 |
| ChEMBL | CHEMBL14249 |
