| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10019972 | HBV | ENSG00000021826.18 | protein_coding | CPS1 | No | No | 1373 | P31327 |
| TVIS10019146 | HBV | ENSG00000021826.18 | protein_coding | CPS1 | No | No | 1373 | P31327 |
| TVIS10020435 | HBV | ENSG00000021826.18 | protein_coding | CPS1 | No | No | 1373 | P31327 |
| TVIS10049876 | HBV | ENSG00000021826.18 | protein_coding | CPS1 | No | No | 1373 | P31327 |
| TVIS10045462 | HBV | ENSG00000021826.18 | protein_coding | CPS1 | No | No | 1373 | P31327 |
| TVIS10045463 | HBV | ENSG00000021826.18 | protein_coding | CPS1 | No | No | 1373 | P31327 |
| TVIS10047041 | HBV | ENSG00000021826.18 | protein_coding | CPS1 | No | No | 1373 | P31327 |
| TVIS10047042 | HBV | ENSG00000021826.18 | protein_coding | CPS1 | No | No | 1373 | P31327 |
| TVIS10047043 | HBV | ENSG00000021826.18 | protein_coding | CPS1 | No | No | 1373 | P31327 |
| TVIS10047044 | HBV | ENSG00000021826.18 | protein_coding | CPS1 | No | No | 1373 | P31327 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CPS1 |
|---|---|
| DrugBank ID | DB06775 |
| Drug Name | Carglumic acid |
| Target ID | BE0004671 |
| UniProt ID | P31327 |
| Regulation Type | allosteric modulator |
| PubMed IDs | 18516804; 19106093; 21207059 |
| Citations | Authors unspecified: Carglumic acid: a second look. Confirmed progress in a rare urea cycle disorder. Prescrire Int. 2008 Apr;17(94):50-1.@@Hart EJ, Powers-Lee SG: Role of Cys-1327 and Cys-1337 in redox sensitivity and allosteric monitoring in human carbamoyl phosphate synthetase. J Biol Chem. 2009 Feb 27;284(9):5977-85. doi: 10.1074/jbc.M808702200. Epub 2008 Dec 23.@@Kasapkara CS, Ezgu FS, Okur I, Tumer L, Biberoglu G, Hasanoglu A: N-carbamylglutamate treatment for acute neonatal hyperammonemia in isovaleric acidemia. Eur J Pediatr. 2011 Jun;170(6):799-801. doi: 10.1007/s00431-010-1362-9. Epub 2011 Jan 5. |
| Groups | Approved |
| Direct Classification | Glutamic acid and derivatives |
| SMILES | NC(=O)N[C@@H](CCC(O)=O)C(O)=O |
| Pathways | |
| PharmGKB | PA165958402 |
| ChEMBL | CHEMBL1201780 |
