| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44044118 | HTLV-1 | ENSG00000162733.19 | protein_coding | DDR2 | Yes | No | 4921 | Q16832 |
| TVIS44037547 | HTLV-1 | ENSG00000162733.19 | protein_coding | DDR2 | Yes | No | 4921 | Q16832 |
| TVIS44037245 | HTLV-1 | ENSG00000162733.19 | protein_coding | DDR2 | Yes | No | 4921 | Q16832 |
| TVIS44043535 | HTLV-1 | ENSG00000162733.19 | protein_coding | DDR2 | Yes | No | 4921 | Q16832 |
| TVIS44044117 | HTLV-1 | ENSG00000162733.19 | protein_coding | DDR2 | Yes | No | 4921 | Q16832 |
| TVIS44043666 | HTLV-1 | ENSG00000162733.19 | protein_coding | DDR2 | Yes | No | 4921 | Q16832 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | DDR2 |
|---|---|
| DrugBank ID | DB00619 |
| Drug Name | Imatinib |
| Target ID | BE0004741 |
| UniProt ID | Q16832 |
| Regulation Type | antagonist |
| PubMed IDs | 18938156 |
| Citations | Day E, Waters B, Spiegel K, Alnadaf T, Manley PW, Buchdunger E, Walker C, Jarai G: Inhibition of collagen-induced discoidin domain receptor 1 and 2 activation by imatinib, nilotinib and dasatinib. Eur J Pharmacol. 2008 Dec 3;599(1-3):44-53. doi: 10.1016/j.ejphar.2008.10.014. Epub 2008 Oct 11. |
| Groups | Approved |
| Direct Classification | Benzanilides |
| SMILES | CN1CCN(CC2=CC=C(C=C2)C(=O)NC2=CC(NC3=NC=CC(=N3)C3=CN=CC=C3)=C(C)C=C2)CC1 |
| Pathways | Imatinib Inhibition of BCR-ABL |
| PharmGKB | PA10804 |
| ChEMBL | CHEMBL941 |
