| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20021186 | HPV | ENSG00000141736.14 | protein_coding | ERBB2 | Yes | No | 2064 | F5H1T4 J3QLU9 P04626 X5DNK3 |
| TVIS20021182 | HPV | ENSG00000141736.14 | protein_coding | ERBB2 | Yes | No | 2064 | F5H1T4 J3QLU9 P04626 X5DNK3 |
| TVIS20016341 | HPV | ENSG00000141736.14 | protein_coding | ERBB2 | Yes | No | 2064 | F5H1T4 J3QLU9 P04626 X5DNK3 |
| TVIS20016342 | HPV | ENSG00000141736.14 | protein_coding | ERBB2 | Yes | No | 2064 | F5H1T4 J3QLU9 P04626 X5DNK3 |
| TVIS20021183 | HPV | ENSG00000141736.14 | protein_coding | ERBB2 | Yes | No | 2064 | F5H1T4 J3QLU9 P04626 X5DNK3 |
| TVIS20021839 | HPV | ENSG00000141736.14 | protein_coding | ERBB2 | Yes | No | 2064 | F5H1T4 J3QLU9 P04626 X5DNK3 |
| TVIS20024092 | HPV | ENSG00000141736.14 | protein_coding | ERBB2 | Yes | No | 2064 | F5H1T4 J3QLU9 P04626 X5DNK3 |
| TVIS20024094 | HPV | ENSG00000141736.14 | protein_coding | ERBB2 | Yes | No | 2064 | F5H1T4 J3QLU9 P04626 X5DNK3 |
| TVIS20017050 | HPV | ENSG00000141736.14 | protein_coding | ERBB2 | Yes | No | 2064 | F5H1T4 J3QLU9 P04626 X5DNK3 |
| TVIS20070298 | HPV | ENSG00000141736.14 | protein_coding | ERBB2 | Yes | No | 2064 | F5H1T4 J3QLU9 P04626 X5DNK3 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ERBB2 |
|---|---|
| DrugBank ID | DB00072 |
| Drug Name | Trastuzumab |
| Target ID | BE0000511 |
| UniProt ID | P04626 |
| Regulation Type | binder |
| PubMed IDs | 11752352; 18690878; 17660958; 11098307 |
| Citations | Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Leveque D, Gigou L, Bergerat JP: Clinical pharmacology of trastuzumab. Curr Clin Pharmacol. 2008 Jan;3(1):51-5.@@Lin A, Rugo HS: The role of trastuzumab in early stage breast cancer: current data and treatment recommendations. Curr Treat Options Oncol. 2007 Feb;8(1):47-60.@@Treish I, Schwartz R, Lindley C: Pharmacology and therapeutic use of trastuzumab in breast cancer. Am J Health Syst Pharm. 2000 Nov 15;57(22):2063-76; quiz 2077-9. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | Trastuzumab Action Pathway |
| PharmGKB | PA451743 |
| ChEMBL | CHEMBL1201585 |
