Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20029779HPVENSG00000113578.18protein_codingFGF1YesNo2246P05230
TVIS20059304HPVENSG00000113578.18protein_codingFGF1YesNo2246P05230
TVIS44031829HTLV-1ENSG00000113578.18protein_codingFGF1YesNo2246P05230
TVIS44025448HTLV-1ENSG00000113578.18protein_codingFGF1YesNo2246P05230
TCGA Plot Options
Drug Information
GeneFGF1
DrugBank IDDB00686
Drug NamePentosan polysulfate
Target IDBE0000689
UniProt IDP05230
Regulation Typeantagonist
PubMed IDs8867461; 8946244; 17071728
CitationsPascu C, Ljungh A, Wadstrom T: Staphylococci bind heparin-binding host growth factors. Curr Microbiol. 1996 Apr;32(4):201-7.@@Zenjari C, Boilly-Marer Y, Desbiens X, Oudghir M, Hondermarck H, Boilly B: Experimental evidence for FGF-1 control of blastema cell proliferation during limb regeneration of the amphibian Pleurodeles waltl. Int J Dev Biol. 1996 Oct;40(5):965-71.@@Jerebtsova M, Wong E, Przygodzki R, Tang P, Ray PE: A novel role of fibroblast growth factor-2 and pentosan polysulfate in the pathogenesis of intestinal bleeding in mice. Am J Physiol Heart Circ Physiol. 2007 Feb;292(2):H743-50. Epub 2006 Oct 27.
GroupsApproved
Direct ClassificationO-glycosyl compounds
SMILESO[C@@H]1CO[C@@H](O[C@@H]2CO[C@@H](O)[C@H](OS(O)(=O)=O)[C@H]2OS(O)(=O)=O)[C@H](OS(O)(=O)=O)[C@H]1OS(O)(=O)=O
Pathways
PharmGKBPA164774806
ChEMBLCHEMBL4073796