| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20067014 | HPV | ENSG00000163288.14 | protein_coding | GABRB1 | No | No | 2560 | P18505 X5DNL6 |
| TVIS44003367 | HTLV-1 | ENSG00000163288.14 | protein_coding | GABRB1 | No | No | 2560 | P18505 X5DNL6 |
| TVIS44015296 | HTLV-1 | ENSG00000163288.14 | protein_coding | GABRB1 | No | No | 2560 | P18505 X5DNL6 |
| TVIS44000681 | HTLV-1 | ENSG00000163288.14 | protein_coding | GABRB1 | No | No | 2560 | P18505 X5DNL6 |
| TVIS44008241 | HTLV-1 | ENSG00000163288.14 | protein_coding | GABRB1 | No | No | 2560 | P18505 X5DNL6 |
| TVIS44022306 | HTLV-1 | ENSG00000163288.14 | protein_coding | GABRB1 | No | No | 2560 | P18505 X5DNL6 |
| TVIS44034552 | HTLV-1 | ENSG00000163288.14 | protein_coding | GABRB1 | No | No | 2560 | P18505 X5DNL6 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GABRB1 |
|---|---|
| DrugBank ID | DB00363 |
| Drug Name | Clozapine |
| Target ID | BE0002344 |
| UniProt ID | P18505 |
| Regulation Type | antagonist |
| PubMed IDs | 8532064; 9016840 |
| Citations | Korpi ER, Wong G, Luddens H: Subtype specificity of gamma-aminobutyric acid type A receptor antagonism by clozapine. Naunyn Schmiedebergs Arch Pharmacol. 1995 Oct;352(4):365-73. doi: 10.1007/BF00172773.@@Squires RF, Saederup E: Clozapine and some other antipsychotic drugs may preferentially block the same subset of GABA(A) receptors. Neurochem Res. 1997 Feb;22(2):151-62. doi: 10.1023/a:1027359422433. |
| Groups | Approved |
| Direct Classification | Dibenzodiazepines |
| SMILES | CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12 |
| Pathways | |
| PharmGKB | PA449061 |
| ChEMBL | CHEMBL42 |
