| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20029384 | HPV | ENSG00000105679.9 | protein_coding | GAPDHS | No | No | 26330 | O14556 |
| TVIS20029385 | HPV | ENSG00000105679.9 | protein_coding | GAPDHS | No | No | 26330 | O14556 |
| TVIS20030204 | HPV | ENSG00000105679.9 | protein_coding | GAPDHS | No | No | 26330 | O14556 |
| TVIS20029386 | HPV | ENSG00000105679.9 | protein_coding | GAPDHS | No | No | 26330 | O14556 |
| TVIS20030205 | HPV | ENSG00000105679.9 | protein_coding | GAPDHS | No | No | 26330 | O14556 |
| TVIS20029387 | HPV | ENSG00000105679.9 | protein_coding | GAPDHS | No | No | 26330 | O14556 |
| TVIS20030206 | HPV | ENSG00000105679.9 | protein_coding | GAPDHS | No | No | 26330 | O14556 |
| TVIS20029388 | HPV | ENSG00000105679.9 | protein_coding | GAPDHS | No | No | 26330 | O14556 |
| TVIS20029389 | HPV | ENSG00000105679.9 | protein_coding | GAPDHS | No | No | 26330 | O14556 |
| TVIS20030207 | HPV | ENSG00000105679.9 | protein_coding | GAPDHS | No | No | 26330 | O14556 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GAPDHS |
|---|---|
| DrugBank ID | DB00157 |
| Drug Name | NADH |
| Target ID | BE0000720 |
| UniProt ID | O14556 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 15488735; 12492483; 16239728 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Maeda K, Nagata H, Nonaka A, Kataoka K, Tanaka M, Shizukuishi S: Oral streptococcal glyceraldehyde-3-phosphate dehydrogenase mediates interaction with Porphyromonas gingivalis fimbriae. Microbes Infect. 2004 Nov;6(13):1163-70.@@Graciet E, Lebreton S, Camadro JM, Gontero B: Characterization of native and recombinant A4 glyceraldehyde 3-phosphate dehydrogenase. Kinetic evidence for confromation changes upon association with the small protein CP12. Eur J Biochem. 2003 Jan;270(1):129-36.@@Ismail SA, Park HW: Structural analysis of human liver glyceraldehyde-3-phosphate dehydrogenase. Acta Crystallogr D Biol Crystallogr. 2005 Nov;61(Pt 11):1508-13. Epub 2005 Oct 19. |
| Groups | Approved; Nutraceutical |
| Direct Classification | (5'->5')-dinucleotides |
| SMILES | NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O |
| Pathways | Ethylmalonic Encephalopathy; 3-Methylglutaconic Aciduria Type III; Short-Chain Acyl-CoA Dehydrogenase Deficiency (SCAD Deficiency); Caffeine Metabolism; Fructose and Mannose Degradation; Isovaleric Aciduria; Lysine Degradation; Methylmalonic Aciduria Due to Cobalamin-Related Disorders; Glycerol Phosphate Shuttle; Zellweger Syndrome; Propionic Acidemia; Glycolysis; Xanthine Dehydrogenase Deficiency (Xanthinuria); S-Adenosylhomocysteine (SAH) Hydrolase Deficiency; Tryptophan Metabolism; Glutaric Aciduria Type I; 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I; Glycine N-Methyltransferase Deficiency; Dimethylglycine Dehydrogenase Deficiency; Androgen and Estrogen Metabolism; Nucleotide Sugars Metabolism; 3-Methylglutaconic Aciduria Type IV; Dihydropyrimidine Dehydrogenase Deficiency (DHPD); Malate-Aspartate Shuttle; Folate Metabolism; Valine, Leucine, and Isoleucine Degradation; Maple Syrup Urine Disease; Glycerol Kinase Deficiency; Adenylosuccinate Lyase Deficiency; Cysteine Metabolism |
| PharmGKB | PA164755085 |
| ChEMBL | CHEMBL1234616 |
