Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10003975HBVENSG00000186469.9protein_codingGNG2NoNo54331P59768
TVIS10011716HBVENSG00000186469.9protein_codingGNG2NoNo54331P59768
TVIS10038213HBVENSG00000186469.9protein_codingGNG2NoNo54331P59768
TVIS10027253HBVENSG00000186469.9protein_codingGNG2NoNo54331P59768
TVIS10046597HBVENSG00000186469.9protein_codingGNG2NoNo54331P59768
TVIS30000758HIVENSG00000186469.9protein_codingGNG2NoNo54331P59768
TVIS30002212HIVENSG00000186469.9protein_codingGNG2NoNo54331P59768
TVIS30002213HIVENSG00000186469.9protein_codingGNG2NoNo54331P59768
TVIS30011887HIVENSG00000186469.9protein_codingGNG2NoNo54331P59768
TVIS30078880HIVENSG00000186469.9protein_codingGNG2NoNo54331P59768
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Drug Information
GeneGNG2
DrugBank IDDB01159
Drug NameHalothane
Target IDBE0001080
UniProt IDP59768
Regulation Typeother/unknown
PubMed IDs10913255; 11961592; 12657848; 12826849; 15175324
CitationsIshizawa Y, Sharp R, Liebman PA, Eckenhoff RG: Halothane binding to a G protein coupled receptor in retinal membranes by photoaffinity labeling. Biochemistry. 2000 Jul 25;39(29):8497-502.@@Zang WJ, Yu XJ, Zang YM: [Effect of halothane on the muscarinic potassium current of the heart]. Sheng Li Xue Bao. 2000 Apr;52(2):175-8.@@Yoshimura H, Jones KA, Perkins WJ, Warner DO: Dual effects of hexanol and halothane on the regulation of calcium sensitivity in airway smooth muscle. Anesthesiology. 2003 Apr;98(4):871-80.@@Streiff J, Jones K, Perkins WJ, Warner DO, Jones KA: Effect of halothane on the guanosine 5' triphosphate binding activity of G-protein alphai subunits. Anesthesiology. 2003 Jul;99(1):105-11.@@Milovic S, Steinecker-Frohnwieser B, Schreibmayer W, Weigl LG: The sensitivity of G protein-activated K+ channels toward halothane is essentially determined by the C terminus. J Biol Chem. 2004 Aug 13;279(33):34240-9. Epub 2004 Jun 2.
GroupsApproved; Vet_approved
Direct ClassificationOrganofluorides
SMILES[H]C(Cl)(Br)C(F)(F)F
Pathways
PharmGKBPA449845
ChEMBLCHEMBL931