| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44027839 | HTLV-1 | ENSG00000171189.18 | protein_coding | GRIK1 | No | No | 2897 | E7ENK3 E7EPY9 E7EPZ0 E9PD61 P39086 |
| TVIS44027840 | HTLV-1 | ENSG00000171189.18 | protein_coding | GRIK1 | No | No | 2897 | E7ENK3 E7EPY9 E7EPZ0 E9PD61 P39086 |
| TVIS44027841 | HTLV-1 | ENSG00000171189.18 | protein_coding | GRIK1 | No | No | 2897 | E7ENK3 E7EPY9 E7EPZ0 E9PD61 P39086 |
| TVIS44018318 | HTLV-1 | ENSG00000171189.18 | protein_coding | GRIK1 | No | No | 2897 | E7ENK3 E7EPY9 E7EPZ0 E9PD61 P39086 |
| TVIS44014010 | HTLV-1 | ENSG00000171189.18 | protein_coding | GRIK1 | No | No | 2897 | E7ENK3 E7EPY9 E7EPZ0 E9PD61 P39086 |
| TVIS44002123 | HTLV-1 | ENSG00000171189.18 | protein_coding | GRIK1 | No | No | 2897 | E7ENK3 E7EPY9 E7EPZ0 E9PD61 P39086 |
| TVIS44035933 | HTLV-1 | ENSG00000171189.18 | protein_coding | GRIK1 | No | No | 2897 | E7ENK3 E7EPY9 E7EPZ0 E9PD61 P39086 |
| TVIS44051687 | HTLV-1 | ENSG00000171189.18 | protein_coding | GRIK1 | No | No | 2897 | E7ENK3 E7EPY9 E7EPZ0 E9PD61 P39086 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GRIK1 |
|---|---|
| DrugBank ID | DB00142 |
| Drug Name | Glutamic acid |
| Target ID | BE0000346 |
| UniProt ID | P39086 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 9254673; 13129570; 10513575 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Sahara Y, Noro N, Iida Y, Soma K, Nakamura Y: Glutamate receptor subunits GluR5 and KA-2 are coexpressed in rat trigeminal ganglion neurons. J Neurosci. 1997 Sep 1;17(17):6611-20.@@Valgeirsson J, Christensen JK, Kristensen AS, Pickering DS, Nielsen B, Fischer CH, Brauner-Osborne H, Nielsen EO, Krogsgaard-Larsen P, Madsen U: Synthesis and in vitro pharmacology at AMPA and kainate preferring glutamate receptors of 4-heteroarylmethylidene glutamate analogues. Bioorg Med Chem. 2003 Oct 1;11(20):4341-9.@@Stensbol TB, Borre L, Johansen TN, Egebjerg J, Madsen U, Ebert B, Krogsgaard-Larsen P: Resolution, absolute stereochemistry and molecular pharmacology of the enantiomers of ATPA. Eur J Pharmacol. 1999 Sep 10;380(2-3):153-62. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Glutamic acid and derivatives |
| SMILES | N[C@@H](CCC(O)=O)C(O)=O |
| Pathways | Histidinemia; Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); 3-Methylglutaconic Aciduria Type I; beta-Ketothiolase Deficiency; Purine Nucleoside Phosphorylase Deficiency; Tyrosine Metabolism; Ketoprofen Action Pathway; Glutamate Metabolism; Argininosuccinic Aciduria; Salla Disease/Infantile Sialic Acid Storage Disease; Tyrosinemia Type I; Hyperinsulinism-Hyperammonemia Syndrome; 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency; Glutaric Aciduria Type I; Propanoate Metabolism; Celecoxib Action Pathway; Glycine and Serine Metabolism; Suprofen Action Pathway; Indomethacin Action Pathway; Carbamoyl Phosphate Synthetase Deficiency; Sialuria or French Type Sialuria; Ibuprofen Action Pathway; Saccharopinuria/Hyperlysinemia II; Histidine Metabolism; Arginine and Proline Metabolism; Purine Metabolism; Diflunisal Action Pathway; Etodolac Action Pathway; Ammonia Recycling |
| PharmGKB | PA449776 |
| ChEMBL | CHEMBL575060 |
