| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44010863 | HTLV-1 | ENSG00000168959.15 | protein_coding | GRM5 | No | No | 2915 | P41594 |
| TVIS44014227 | HTLV-1 | ENSG00000168959.15 | protein_coding | GRM5 | No | No | 2915 | P41594 |
| TVIS44009186 | HTLV-1 | ENSG00000168959.15 | protein_coding | GRM5 | No | No | 2915 | P41594 |
| TVIS44006233 | HTLV-1 | ENSG00000168959.15 | protein_coding | GRM5 | No | No | 2915 | P41594 |
| TVIS44017415 | HTLV-1 | ENSG00000168959.15 | protein_coding | GRM5 | No | No | 2915 | P41594 |
| TVIS44026684 | HTLV-1 | ENSG00000168959.15 | protein_coding | GRM5 | No | No | 2915 | P41594 |
| TVIS44040855 | HTLV-1 | ENSG00000168959.15 | protein_coding | GRM5 | No | No | 2915 | P41594 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GRM5 |
|---|---|
| DrugBank ID | DB00659 |
| Drug Name | Acamprosate |
| Target ID | BE0001192 |
| UniProt ID | P41594 |
| Regulation Type | antagonist |
| PubMed IDs | 15963001; 18377703 |
| Citations | De Witte P, Littleton J, Parot P, Koob G: Neuroprotective and abstinence-promoting effects of acamprosate: elucidating the mechanism of action. CNS Drugs. 2005;19(6):517-37.@@Blednov YA, Harris RA: Metabotropic glutamate receptor 5 (mGluR5) regulation of ethanol sedation, dependence and consumption: relationship to acamprosate actions. Int J Neuropsychopharmacol. 2008 Sep;11(6):775-93. doi: 10.1017/S1461145708008584. Epub 2008 Apr 1. |
| Groups | Approved; Investigational |
| Direct Classification | Organosulfonic acids |
| SMILES | CC(=O)NCCCS(O)(=O)=O |
| Pathways | |
| PharmGKB | PA10344 |
| ChEMBL | CHEMBL1201293 |
