| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20019218 | HPV | ENSG00000137252.10 | protein_coding | HCRTR2 | No | No | 3062 | O43614 S4X0W3 |
| TVIS20061206 | HPV | ENSG00000137252.10 | protein_coding | HCRTR2 | No | No | 3062 | O43614 S4X0W3 |
| TVIS44033822 | HTLV-1 | ENSG00000137252.10 | protein_coding | HCRTR2 | No | No | 3062 | O43614 S4X0W3 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HCRTR2 |
|---|---|
| DrugBank ID | DB09034 |
| Drug Name | Suvorexant |
| Target ID | BE0005865 |
| UniProt ID | O43614 |
| Regulation Type | antagonist |
| PubMed IDs | 23702225 |
| Citations | Palasz A, Lapray D, Peyron C, Rojczyk-Golebiewska E, Skowronek R, Markowski G, Czajkowska B, Krzystanek M, Wiaderkiewicz R: Dual orexin receptor antagonists - promising agents in the treatment of sleep disorders. Int J Neuropsychopharmacol. 2014 Jan;17(1):157-68. doi: 10.1017/S1461145713000552. Epub 2013 May 23. |
| Groups | Approved; Investigational |
| Direct Classification | N,N-dialkyl-m-toluamides |
| SMILES | [H][C@@]1(C)CCN(CCN1C(=O)C1=C(C=CC(C)=C1)N1N=CC=N1)C1=NC2=C(O1)C=CC(Cl)=C2 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1083659 |
