| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44037563 | HTLV-1 | ENSG00000160712.13 | protein_coding | IL6R | No | No | 3570 | A0A087WTB5 A0N0L5 P08887 |
| TVIS44050039 | HTLV-1 | ENSG00000160712.13 | protein_coding | IL6R | No | No | 3570 | A0A087WTB5 A0N0L5 P08887 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | IL6R |
|---|---|
| DrugBank ID | DB06273 |
| Drug Name | Tocilizumab |
| Target ID | BE0002859 |
| UniProt ID | P08887 |
| Regulation Type | inhibitor |
| PubMed IDs | 16899109; 21940820 |
| Citations | Smolen JS, Maini RN: Interleukin-6: a new therapeutic target. Arthritis Res Ther. 2006;8 Suppl 2:S5. Epub 2006 Jul 28.@@Betts BC, St Angelo ET, Kennedy M, Young JW: Anti-IL6-receptor-alpha (tocilizumab) does not inhibit human monocyte-derived dendritic cell maturation or alloreactive T-cell responses. Blood. 2011 Nov 10;118(19):5340-3. doi: 10.1182/blood-2011-06-363390. Epub 2011 Sep 22. |
| Groups | Approved |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA165292659 |
| ChEMBL | CHEMBL1237022 |
