Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44043653HTLV-1ENSG00000082482.14protein_codingKCNK2NoNo3776O95069
Q6ZW95
U3N6F0
U3N834
TVIS44044002HTLV-1ENSG00000082482.14protein_codingKCNK2NoNo3776O95069
Q6ZW95
U3N6F0
U3N834
TVIS44043652HTLV-1ENSG00000082482.14protein_codingKCNK2NoNo3776O95069
Q6ZW95
U3N6F0
U3N834
TVIS44037142HTLV-1ENSG00000082482.14protein_codingKCNK2NoNo3776O95069
Q6ZW95
U3N6F0
U3N834
TVIS44035345HTLV-1ENSG00000082482.14protein_codingKCNK2NoNo3776O95069
Q6ZW95
U3N6F0
U3N834
TCGA Plot Options
Drug Information
GeneKCNK2
DrugBank IDDB00204
Drug NameDofetilide
Target IDBE0000210
UniProt IDO95069
Regulation Typeinhibitor
PubMed IDs17139284; 17016423; 17187453
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Roukoz H, Saliba W: Dofetilide: a new class III antiarrhythmic agent. Expert Rev Cardiovasc Ther. 2007 Jan;5(1):9-19.
GroupsApproved; Investigational
Direct ClassificationSulfanilides
SMILESCN(CCOC1=CC=C(NS(C)(=O)=O)C=C1)CCC1=CC=C(NS(C)(=O)=O)C=C1
Pathways
PharmGKBPA449389
ChEMBLCHEMBL473