| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10014444 | HBV | ENSG00000081479.15 | protein_coding | LRP2 | No | No | 4036 | P98164 |
| TVIS10001909 | HBV | ENSG00000081479.15 | protein_coding | LRP2 | No | No | 4036 | P98164 |
| TVIS10001910 | HBV | ENSG00000081479.15 | protein_coding | LRP2 | No | No | 4036 | P98164 |
| TVIS10023422 | HBV | ENSG00000081479.15 | protein_coding | LRP2 | No | No | 4036 | P98164 |
| TVIS10028751 | HBV | ENSG00000081479.15 | protein_coding | LRP2 | No | No | 4036 | P98164 |
| TVIS10023421 | HBV | ENSG00000081479.15 | protein_coding | LRP2 | No | No | 4036 | P98164 |
| TVIS10028752 | HBV | ENSG00000081479.15 | protein_coding | LRP2 | No | No | 4036 | P98164 |
| TVIS30012764 | HIV | ENSG00000081479.15 | protein_coding | LRP2 | No | No | 4036 | P98164 |
| TVIS20002372 | HPV | ENSG00000081479.15 | protein_coding | LRP2 | No | No | 4036 | P98164 |
| TVIS20033461 | HPV | ENSG00000081479.15 | protein_coding | LRP2 | No | No | 4036 | P98164 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | LRP2 |
|---|---|
| DrugBank ID | DB00013 |
| Drug Name | Urokinase |
| Target ID | BE0000942 |
| UniProt ID | P98164 |
| Regulation Type | substrate |
| PubMed IDs | 17139284; 17016423; 8241286; 1280065; 7959795 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Kanalas JJ: Effect of the nephritogenic autoantibody of Heymann's nephritis on plasminogen-binding to gp330 and activation by urokinase. Biochim Biophys Acta. 1993 Nov 25;1225(1):101-6.@@Kanalas JJ: Analysis of plasmin binding and urokinase activation of plasminogen bound to the Heymann nephritis autoantigen, gp330. Arch Biochem Biophys. 1992 Dec;299(2):255-60.@@Korenberg JR, Argraves KM, Chen XN, Tran H, Strickland DK, Argraves WS: Chromosomal localization of human genes for the LDL receptor family member glycoprotein 330 (LRP2) and its associated protein RAP (LRPAP1). Genomics. 1994 Jul 1;22(1):88-93. |
| Groups | Approved; Investigational; Withdrawn |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | Urokinase Action Pathway |
| PharmGKB | PA451836 |
| ChEMBL | CHEMBL1201420 |
