| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20066834 | HPV | ENSG00000100030.15 | protein_coding | MAPK1 | Yes | No | 5594 | P28482 Q1HBJ4 Q499G7 |
| TVIS20068128 | HPV | ENSG00000100030.15 | protein_coding | MAPK1 | Yes | No | 5594 | P28482 Q1HBJ4 Q499G7 |
| TVIS20066130 | HPV | ENSG00000100030.15 | protein_coding | MAPK1 | Yes | No | 5594 | P28482 Q1HBJ4 Q499G7 |
| TVIS20020649 | HPV | ENSG00000100030.15 | protein_coding | MAPK1 | Yes | No | 5594 | P28482 Q1HBJ4 Q499G7 |
| TVIS20020650 | HPV | ENSG00000100030.15 | protein_coding | MAPK1 | Yes | No | 5594 | P28482 Q1HBJ4 Q499G7 |
| TVIS44008948 | HTLV-1 | ENSG00000100030.15 | protein_coding | MAPK1 | Yes | No | 5594 | P28482 Q1HBJ4 Q499G7 |
| TVIS44024155 | HTLV-1 | ENSG00000100030.15 | protein_coding | MAPK1 | Yes | No | 5594 | P28482 Q1HBJ4 Q499G7 |
| TVIS44035634 | HTLV-1 | ENSG00000100030.15 | protein_coding | MAPK1 | Yes | No | 5594 | P28482 Q1HBJ4 Q499G7 |
| TVIS44051718 | HTLV-1 | ENSG00000100030.15 | protein_coding | MAPK1 | Yes | No | 5594 | P28482 Q1HBJ4 Q499G7 |
| TVIS44051719 | HTLV-1 | ENSG00000100030.15 | protein_coding | MAPK1 | Yes | No | 5594 | P28482 Q1HBJ4 Q499G7 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | MAPK1 |
|---|---|
| DrugBank ID | DB01017 |
| Drug Name | Minocycline |
| Target ID | BE0009853 |
| UniProt ID | P45984 |
| Regulation Type | inhibitor |
| PubMed IDs | 11986668 |
| Citations | Zhu S, Stavrovskaya IG, Drozda M, Kim BY, Ona V, Li M, Sarang S, Liu AS, Hartley DM, Wu DC, Gullans S, Ferrante RJ, Przedborski S, Kristal BS, Friedlander RM: Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice. Nature. 2002 May 2;417(6884):74-8. |
| Groups | Approved; Investigational |
| Direct Classification | Tetracyclines |
| SMILES | [H][C@@]12CC3=C(C(O)=CC=C3N(C)C)C(=O)C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@]1([H])C2 |
| Pathways | Minocycline Action Pathway |
| PharmGKB | PA450519 |
| ChEMBL | CHEMBL1434 |
