| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20042226 | HPV | ENSG00000107643.17 | protein_coding | MAPK8 | No | No | 5599 | A1L4K2 P45983 |
| TVIS20048727 | HPV | ENSG00000107643.17 | protein_coding | MAPK8 | No | No | 5599 | A1L4K2 P45983 |
| TVIS20049028 | HPV | ENSG00000107643.17 | protein_coding | MAPK8 | No | No | 5599 | A1L4K2 P45983 |
| TVIS44008648 | HTLV-1 | ENSG00000107643.17 | protein_coding | MAPK8 | No | No | 5599 | A1L4K2 P45983 |
| TVIS44034357 | HTLV-1 | ENSG00000107643.17 | protein_coding | MAPK8 | No | No | 5599 | A1L4K2 P45983 |
| TVIS44046431 | HTLV-1 | ENSG00000107643.17 | protein_coding | MAPK8 | No | No | 5599 | A1L4K2 P45983 |
| TVIS44040446 | HTLV-1 | ENSG00000107643.17 | protein_coding | MAPK8 | No | No | 5599 | A1L4K2 P45983 |
| TVIS44040618 | HTLV-1 | ENSG00000107643.17 | protein_coding | MAPK8 | No | No | 5599 | A1L4K2 P45983 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MAPK8 |
|---|---|
| DrugBank ID | DB00675 |
| Drug Name | Tamoxifen |
| Target ID | BE0003790 |
| UniProt ID | P45983 |
| Regulation Type | modulator |
| PubMed IDs | 27083550 |
| Citations | Radin DP, Patel P: Delineating the molecular mechanisms of tamoxifen's oncolytic actions in estrogen receptor-negative cancers. Eur J Pharmacol. 2016 Jun 15;781:173-80. doi: 10.1016/j.ejphar.2016.04.017. Epub 2016 Apr 12. |
| Groups | Approved |
| Direct Classification | Stilbenes |
| SMILES | CCC(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1 |
| Pathways | Tamoxifen Metabolism Pathway; Tamoxifen Action Pathway |
| PharmGKB | PA451581 |
| ChEMBL | CHEMBL83 |
