| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20015780 | HPV | ENSG00000136997.22 | protein_coding | MYC | Yes | No | 4609 | P01106 |
| TVIS20020386 | HPV | ENSG00000136997.22 | protein_coding | MYC | Yes | No | 4609 | P01106 |
| TVIS20020704 | HPV | ENSG00000136997.22 | protein_coding | MYC | Yes | No | 4609 | P01106 |
| TVIS20020705 | HPV | ENSG00000136997.22 | protein_coding | MYC | Yes | No | 4609 | P01106 |
| TVIS20020706 | HPV | ENSG00000136997.22 | protein_coding | MYC | Yes | No | 4609 | P01106 |
| TVIS20020707 | HPV | ENSG00000136997.22 | protein_coding | MYC | Yes | No | 4609 | P01106 |
| TVIS20020608 | HPV | ENSG00000136997.22 | protein_coding | MYC | Yes | No | 4609 | P01106 |
| TVIS20020609 | HPV | ENSG00000136997.22 | protein_coding | MYC | Yes | No | 4609 | P01106 |
| TVIS20020610 | HPV | ENSG00000136997.22 | protein_coding | MYC | Yes | No | 4609 | P01106 |
| TVIS20020611 | HPV | ENSG00000136997.22 | protein_coding | MYC | Yes | No | 4609 | P01106 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | MYC |
|---|---|
| DrugBank ID | DB00945 |
| Drug Name | Acetylsalicylic acid |
| Target ID | BE0004689 |
| UniProt ID | P01106 |
| Regulation Type | downregulator |
| PubMed IDs | 10993886; 28415819; 26314861 |
| Citations | Law BK, Waltner-Law ME, Entingh AJ, Chytil A, Aakre ME, Norgaard P, Moses HL: Salicylate-induced growth arrest is associated with inhibition of p70s6k and down-regulation of c-myc, cyclin D1, cyclin A, and proliferating cell nuclear antigen. J Biol Chem. 2000 Dec 8;275(49):38261-7. doi: 10.1074/jbc.M005545200.@@Cheng R, Liu YJ, Cui JW, Yang M, Liu XL, Li P, Wang Z, Zhu LZ, Lu SY, Zou L, Wu XQ, Li YX, Zhou Y, Fang ZY, Wei W: Aspirin regulation of c-myc and cyclinD1 proteins to overcome tamoxifen resistance in estrogen receptor-positive breast cancer cells. Oncotarget. 2017 May 2;8(18):30252-30264. doi: 10.18632/oncotarget.16325.@@Ai G, Dachineni R, Muley P, Tummala H, Bhat GJ: Aspirin and salicylic acid decrease c-Myc expression in cancer cells: a potential role in chemoprevention. Tumour Biol. 2016 Feb;37(2):1727-38. doi: 10.1007/s13277-015-3959-0. Epub 2015 Aug 28. |
| Groups | Approved; Vet_approved |
| Direct Classification | Acylsalicylic acids |
| SMILES | CC(=O)OC1=CC=CC=C1C(O)=O |
| Pathways | Acetylsalicylic Acid Action Pathway |
| PharmGKB | PA448497 |
| ChEMBL | CHEMBL25 |
