| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44050822 | HTLV-1 | ENSG00000122884.13 | protein_coding | P4HA1 | No | No | 5033 | P13674 Q5VSQ6 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | P4HA1 |
|---|---|
| DrugBank ID | DB00126 |
| Drug Name | Ascorbic acid |
| Target ID | BE0000060 |
| UniProt ID | P13674 |
| Regulation Type | cofactor |
| PubMed IDs | 29289682 |
| Citations | Osipyants AI, Poloznikov AA, Smirnova NA, Hushpulian DM, Khristichenko AY, Chubar TA, Zakhariants AA, Ahuja M, Gaisina IN, Thomas B, Brown AM, Gazaryan IG, Tishkov VI: L-ascorbic acid: A true substrate for HIF prolyl hydroxylase? Biochimie. 2018 Apr;147:46-54. doi: 10.1016/j.biochi.2017.12.011. Epub 2017 Dec 28. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Butenolides |
| SMILES | [H][C@@]1(OC(=O)C(O)=C1O)[C@@H](O)CO |
| Pathways | Tyrosine Metabolism; Refsum Disease; The Oncogenic Action of Succinate; Disulfiram Action Pathway; Aromatic L-Aminoacid Decarboxylase Deficiency; Oxidation of Branched-Chain Fatty Acids; Catecholamine Biosynthesis; Monoamine Oxidase-A Deficiency (MAO-A); Tyrosinemia, Transient, of the Newborn; Carnitine Synthesis; Phytanic Acid Peroxisomal Oxidation; Hawkinsinuria; Dopamine beta-Hydroxylase Deficiency; Tyrosinemia Type I; Alkaptonuria; Tyrosine Hydroxylase Deficiency; The Oncogenic Action of Fumarate |
| PharmGKB | PA451898 |
| ChEMBL | CHEMBL196 |
