| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20045192 | HPV | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
| TVIS20027548 | HPV | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
| TVIS20060875 | HPV | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
| TVIS44016592 | HTLV-1 | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
| TVIS44022542 | HTLV-1 | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
| TVIS44025677 | HTLV-1 | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
| TVIS44005267 | HTLV-1 | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
| TVIS44034604 | HTLV-1 | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
| TVIS44039118 | HTLV-1 | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
| TVIS44039278 | HTLV-1 | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE10A |
|---|---|
| DrugBank ID | DB00975 |
| Drug Name | Dipyridamole |
| Target ID | BE0000631 |
| UniProt ID | Q9Y233 |
| Regulation Type | inhibitor |
| PubMed IDs | 17139284; 17016423; 10373451 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Fujishige K, Kotera J, Michibata H, Yuasa K, Takebayashi S, Okumura K, Omori K: Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A). J Biol Chem. 1999 Jun 25;274(26):18438-45. |
| Groups | Approved |
| Direct Classification | Dialkylarylamines |
| SMILES | OCCN(CCO)C1=NC2=C(N=C(N=C2N2CCCCC2)N(CCO)CCO)C(=N1)N1CCCCC1 |
| Pathways | Dipyridamole (Antiplatelet) Action Pathway |
| PharmGKB | PA449367 |
| ChEMBL | CHEMBL932 |
