| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30029102 | HIV | ENSG00000152270.9 | protein_coding | PDE3B | No | No | 5140 | A7E2E5 Q13370 |
| TVIS30017920 | HIV | ENSG00000152270.9 | protein_coding | PDE3B | No | No | 5140 | A7E2E5 Q13370 |
| TVIS20008942 | HPV | ENSG00000152270.9 | protein_coding | PDE3B | No | No | 5140 | A7E2E5 Q13370 |
| TVIS20049437 | HPV | ENSG00000152270.9 | protein_coding | PDE3B | No | No | 5140 | A7E2E5 Q13370 |
| TVIS20043543 | HPV | ENSG00000152270.9 | protein_coding | PDE3B | No | No | 5140 | A7E2E5 Q13370 |
| TVIS20017444 | HPV | ENSG00000152270.9 | protein_coding | PDE3B | No | No | 5140 | A7E2E5 Q13370 |
| TVIS44003566 | HTLV-1 | ENSG00000152270.9 | protein_coding | PDE3B | No | No | 5140 | A7E2E5 Q13370 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE3B |
|---|---|
| DrugBank ID | DB01427 |
| Drug Name | Amrinone |
| Target ID | BE0001223 |
| UniProt ID | Q13370 |
| Regulation Type | inhibitor |
| PubMed IDs | 19060915; 17332439; 24930515 |
| Citations | Rao YJ, Xi L: Pivotal effects of phosphodiesterase inhibitors on myocyte contractility and viability in normal and ischemic hearts. Acta Pharmacol Sin. 2009 Jan;30(1):1-24. doi: 10.1038/aps.2008.1. Epub 2008 Dec 8.@@Yan C, Miller CL, Abe J: Regulation of phosphodiesterase 3 and inducible cAMP early repressor in the heart. Circ Res. 2007 Mar 2;100(4):489-501. doi: 10.1161/01.RES.0000258451.44949.d7.@@Zywert A, Szkudelska K, Szkudelski T: Inhibition of phosphodiesterase 3B in insulin-secreting cells of normal and streptozocin-nicotinamide-induced diabetic rats: implications for insulin secretion. J Physiol Pharmacol. 2014 Jun;65(3):425-33. |
| Groups | Approved |
| Direct Classification | Bipyridines and oligopyridines |
| SMILES | NC1=CC(=CNC1=O)C1=CC=NC=C1 |
| Pathways | |
| PharmGKB | PA164746803 |
| ChEMBL | CHEMBL12856 |
