| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44009694 | HTLV-1 | ENSG00000116711.10 | protein_coding | PLA2G4A | No | No | 5321 | P47712 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PLA2G4A |
|---|---|
| DrugBank ID | DB00588 |
| Drug Name | Fluticasone propionate |
| Target ID | BE0000657 |
| UniProt ID | P47712 |
| Regulation Type | inhibitor |
| PubMed IDs | 10351938; 15083746 |
| Citations | Sano A, Munoz NM, Sano H, Choi J, Zhu X, Jacobs B, Leff AR: Inhibition of cPLA2 translocation and leukotriene C4 secretion by fluticasone propionate in exogenously activated human eosinophils. Am J Respir Crit Care Med. 1999 Jun;159(6):1903-9.@@Myo S, Zhu X, Myou S, Meliton AY, Liu J, Boetticher E, Lambertino AT, Xu C, Munoz NM, Leff AR: Additive blockade of beta 2-integrin adhesion of eosinophils by salmeterol and fluticasone propionate. Eur Respir J. 2004 Apr;23(4):511-7. |
| Groups | Approved |
| Direct Classification | Steroid esters |
| SMILES | [H][C@@]12C[C@@H](C)[C@](OC(=O)CC)(C(=O)SCF)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C |
| Pathways | |
| PharmGKB | PA449686 |
| ChEMBL | CHEMBL1473 |
