| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44037251 | HTLV-1 | ENSG00000083444.17 | protein_coding | PLOD1 | No | No | 5351 | Q02809 |
| TVIS44044184 | HTLV-1 | ENSG00000083444.17 | protein_coding | PLOD1 | No | No | 5351 | Q02809 |
| TVIS44044183 | HTLV-1 | ENSG00000083444.17 | protein_coding | PLOD1 | No | No | 5351 | Q02809 |
| TVIS44044182 | HTLV-1 | ENSG00000083444.17 | protein_coding | PLOD1 | No | No | 5351 | Q02809 |
| TVIS44037653 | HTLV-1 | ENSG00000083444.17 | protein_coding | PLOD1 | No | No | 5351 | Q02809 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PLOD1 |
|---|---|
| DrugBank ID | DB00126 |
| Drug Name | Ascorbic acid |
| Target ID | BE0000087 |
| UniProt ID | Q02809 |
| Regulation Type | cofactor |
| PubMed IDs | 17100196; 11752352; 9344473 |
| Citations | Salavoura K, Valari M, Kolialexi A, Mavrou A, Kitsiou S: A case of Ehlers Danlos syndrome type VI. Genet Couns. 2006;17(3):291-4.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Yeowell HN, Walker LC, Murad S, Pinnell SR: A common duplication in the lysyl hydroxylase gene of patients with Ehlers Danlos syndrome type VI results in preferential stimulation of lysyl hydroxylase activity and mRNA by hydralazine. Arch Biochem Biophys. 1997 Nov 1;347(1):126-31. doi: 10.1006/abbi.1997.0319. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Butenolides |
| SMILES | [H][C@@]1(OC(=O)C(O)=C1O)[C@@H](O)CO |
| Pathways | Tyrosine Metabolism; Refsum Disease; The Oncogenic Action of Succinate; Disulfiram Action Pathway; Aromatic L-Aminoacid Decarboxylase Deficiency; Oxidation of Branched-Chain Fatty Acids; Catecholamine Biosynthesis; Monoamine Oxidase-A Deficiency (MAO-A); Tyrosinemia, Transient, of the Newborn; Carnitine Synthesis; Phytanic Acid Peroxisomal Oxidation; Hawkinsinuria; Dopamine beta-Hydroxylase Deficiency; Tyrosinemia Type I; Alkaptonuria; Tyrosine Hydroxylase Deficiency; The Oncogenic Action of Fumarate |
| PharmGKB | PA451898 |
| ChEMBL | CHEMBL196 |
